| File
name
|
MoIHCCarney.[ch]
|
| Description
|
Laurel
H. Carney inner hair cell (IHC) synapse module ([3.]). It requires an
IHC receptor potential module as input (e.g. see IHCRP_Carney: Inner Hair Cell
Receptor Potential (1993), page 215). It outputs spike probabilities.
|
| Example
parameter file format
|
100e-3 Endocochlear potential, Et (V). -49e-3 Reversal potential, Ek (V). 0.04 Reversal potential correction, Rp/(Rt+Rp). 6.21e-12 Total capacitance, C = Ca + Cb (F). 0.0868e-8 Resting conductance, G0 (S). 1.430e-8 Potassium conductance, Gk (S = Siemens). 0.398e-8 Maximum mechanical conductance, Gmax (S). 0.25 Beta constant, exp(-G1/RT). 10e+6 Gamma constant, Z1/RT (/m). 0.656e-3 Cilia/BM time constant (s). -77.5 Cilia/BM coupling gain, C (dB). -0.0367 Reference potential (V). |
| Test
program directory
|
Tests/Models/Transduction/Hair_Cell,
Tests/SSPrograms
|
| Syntax
|
BOOLN RunModel_IHC_Carney(EarObjectPtr data);
|
| Returns
|
TRUE
if the process is successful, otherwise it returns FALSE.
|
| Syntax
|
BOOLN SetMaxGlobalPerm_IHC_Carney(double
theMaxGlobalPerm);
|
| Returns
|
TRUE
if the function is successful, otherwise it returns FALSE.
|
| Syntax
|
BOOLN SetMaxHCVoltage_IHC_Carney(double
theMaxHCVoltage);
|
| Returns
|
TRUE
if the function is successful, otherwise it returns FALSE.
|
| Syntax
|
BOOLN SetMaxImmediatePerm_IHC_Carney(double
theMaxImmediatePerm);
|
| Returns
|
TRUE
if the function is successful, otherwise it returns FALSE.
|
| Syntax
|
BOOLN SetMaxImmediateVolume_IHC_Carney(double
theMaxImmediateVolume);
|
| Returns
|
TRUE
if the function is successful, otherwise it returns FALSE.
|
| Syntax
|
BOOLN SetMaxLocalPerm_IHC_Carney(double
theMaxLocalPerm);
|
| Returns
|
TRUE
if the function is successful, otherwise it returns FALSE.
|
| Syntax
|
BOOLN SetMaxLocalVolume_IHC_Carney(double
theMaxLocalVolume);
|
| Returns
|
TRUE
if the function is successful, otherwise it returns FALSE.
|
| Syntax
|
BOOLN SetMinImmediateVolume_IHC_Carney(double
theMinImmediateVolume);
|
| Returns
|
TRUE
if the function is successful, otherwise it returns FALSE.
|
| Syntax
|
BOOLN SetMinLocalVolume_IHC_Carney(double
theMinLocalVolume);
|
| Returns
|
TRUE
if the function is successful, otherwise it returns FALSE.
|
| Syntax
|
BOOLN SetPars_IHC_Carney(double maxHCVoltage,
double restingReleaseRate, double restingPerm, double
maxGlobalPerm, double maxLocalPerm, double
maxImmediatePerm, double maxLocalVolume, double
minLocalVolume, double maxImmediateVolume, double
minImmediateVolume);
|
| Returns
|
TRUE
if the function is successful, otherwise it returns FALSE.
|
| Syntax
|
BOOLN SetRestingPerm_IHC_Carney(double
theRestingPerm);
|
| Returns
|
TRUE
if the function is successful, otherwise it returns FALSE.
|
| Syntax
|
BOOLN SetRestingReleaseRate_IHC_Carney(double
theRestingReleaseRate);
|
| Returns
|
TRUE
if the function is successful, otherwise it returns FALSE.
|
# # Main Parameter file # output.dat Name of output file. # Module specifications. #Par. file Name Description #--------- ----- ------------- PTone1.par PureTone Stimulus generation paradigm. GPigChinPE.par null Outer-/middler-ear filter model. Carney1k.par BasilarM_Carney basilar membrane filter model. CarneyRP1.par IHCRP_Carney IHC receptor potential model. CarneyIHC1.par IHC_Carney Inner hair cell (IHC) model. SpikeGn1.par null Auditory nerve spike generation. Dendrite3.par null Dendritic filtering. MG0Stellate.par null Neural cell model. Histogm1.par Histogram module parameter file. # Miscellaneous parameters 1 Number of model runs. 125.0 Initial stimulus frequency (Hz). 10000.0 Final stimulus frequency (Hz). 10 Number of frequency readings readings. 2.5e-3 Ramp up rise time for signal (s).
Figure [89] Firing characteristics for the LUTEar AN models in
relation to changing frequency.
# # Main Parameter file # output.dat Name of output file. # Module specifications. #Par. file Name Description #--------- ----- ------------- PTone1.par PureTone Stimulus generation paradigm. GPigChinPE.par null Outer-/middler-ear filter model. Carney1k.par BasilarM_Carney basilar membrane filter model. CarneyRP1.par IHCRP_Carney IHC receptor potential model. CarneyIHC1.par IHC_Carney Inner hair cell (IHC) model. SpikeGn1.par null Auditory nerve spike generation. Dendrite3.par null Dendritic filtering. MG0Stellate.par null Neural cell model. Histogm1.par Histogram module parameter file. # Miscellaneous parameters 10 Number of analysis readings. 1 Number of model runs. 1000.0 Stimulus frequency (Hz). -40.0 Initial stimulus signal intensity (dB SPL). 10.0 Intensity increment for successive readings (dB). 2.5e-3 Ramp up rise time for signal (s).
Figure [90] Firing characteristics for the Carney AN model in
relation to changing intensity.
Figure [91] Synchronisation characteristics for the LUTEar AN
models in relation to changing intensity.
Example: Tests/Models/Transduction/Hair_Cell/RateIntensity.c
Parameter file:RateIntensity.par:
#
# Main Parameter file
#
output.dat Name of output file.
# Module specifications.
#Par. file Name Description
#--------- ----- -------------
PTone2.par PureTone Stimulus generation paradigm.
GPigChinPE.par null Outer-/middler-ear filter model.
Carney1k.par BasilarM_Carney basilar membrane filter model.
CarneyRP1.par IHCRP_Carney IHC receptor potential model.
CarneyIHC1.par IHC_Carney Inner hair cell (IHC) model.
Carney1SG.par null Auditory nerve spike generation.
Dendrite3.par null Dendritic filtering.
MG0Stellate.par null Neural cell model.
Histogm2.par Histogram module parameter file.
FindBin1.par Find maximum bin values analysis module parameter file.
# Miscellaneous parameters
10 Number of analysis readings.
1 Number of model runs.
1 Number of fibre responses (IHC -> AnN repeats).
0.0 Initial stimulus signal intensity (dB SPL).
10 Intensity increment for successive readings (dB).
2.5e-3 Ramp up rise time for signal (s).
Output
Figure [92] Rate-intensity functions for the Carney AN
model.
Figure [93] Rate-intensity functions for the Carney AN model.
Note that the main parameter file was changed to produce this diagram: the
"ANSpikeGen_Carney" module was put in (using the "Carney1SG.par" module
parameter file, the "Histogm2.par" module parameter file was replaced by
"Histogm4.par" and the number of model runs was set to 200.
Figure [94] Firing characteristics comparison for the LUTEar
AN models. (Created using the test program "PLockvsInt.c".)
Example: Tests/SSPrograms/ModelResp.c
Parameter file:ModelResp.par:
#
# SimulationSpec main parameter file.
#
output.dat Output file.
SimSpecs/IHC/CarneyHist.sim Simulation Specification file.
# Misc. parameters.
1 Number of repeat runs.
Output
Figure [95] Post stimulus time histogram (PSTH) for the Carney
AN model.
Example: Tests/Models/Transduction/Hair_Cell/TwoCAdapt.c
Parameter file:TwoCAdapt.par:
#
# Main Parameter file
#
output.dat Name of output file.
# Module specifications.
#Par. file Name Description
#--------- ----- -------------
PTone3.par PureTone Stimulus generation paradigm.
GPigChinPE.par null Outer-/middler-ear filter model.
Carney1k.par BasilarM_Carney basilar membrane filter model.
CarneyRP1.par IHCRP_Carney IHC receptor potential model.
CarneyIHC1.par IHC_Carney Inner hair cell (IHC) model.
Carney1SG.par null Auditory nerve spike generation.
Dendrite3.par null Dendritic filtering.
MG0Stellate.par null Neural cell model.
Histogm1.par Histogram module parameter file.
# Miscellaneous parameters
9 Number of analysis readings.
1 Number of model runs.
1 Number of fibre responses (IHC -> AnN repeats).
20.0 Initial stimulus signal intensity (dB SPL).
10.0 Intensity increment for successive readings (dB).
2.5e-3 Ramp up rise time for signal (s).
3.0e-3 Short-term time, T1 for approximation calculation. (s).
40.0e-3 Short-term period for approximation calculation (s).
2.0e-3 Rapid adapt period for approximation calculation.
Output
Figure [96] Two-component adaptation characteristics for the
Carney AN model.
Example: Tests/Models/Transduction/Hair_Cell/TwoTSuppress.c
Parameter file:TwoTSuppress.par:
#
# Main Parameter file
#
output.dat Name of output file.
# Module specifications.
#Par. file Name Description
#--------- ----- -------------
MPTone2.par PureTone_Multi Stimulus generation paradigm.
GPigChinPE.par null Outer-/middler-ear filter model.
Carney1k.par BasilarM_Carney basilar membrane filter model.
CarneyRP1.par IHCRP_Carney IHC receptor potential model.
CarneyIHC1.par IHC_Carney Inner hair cell (IHC) model.
Carney1SG.par null Auditory nerve spike generation.
Dendrite3.par null Dendritic filtering.
MG0Stellate.par null Neural cell model.
Histogm1.par Histogram module parameter file.
# Miscellaneous parameters
20 Number of test frequencies.
1 Number of model runs.
2000.0 Lowest test frequency (Hz).
15170.0 Highest test frequency (Hz).
80.0 Test pure tone initial intensity (dB SPL).
0.0 Final test stimulus Intensity step (dB SPL).
10.0 Test stimulus intensity decrement (dB).
2.5e-3 Ramp up rise time for signal (s).
Output
Figure [97] Two-tone suppression characteristics for the
Carney AN model.