Publications

 

NV Cozzi, A Gopalakrishnan, LL Anderson, JT Feih, AT Shulgin, PF Daley, AE Ruoho.  Dimethyltryptamine and other hallucinogenic tryptamines exhibit substrate behavior at the serotonin uptake transporter and the vesicle monoamine transporter.  J. Neural Transm., 116, 1591-1599 (2009)

 

LW Guo, AR Hajipour, NV Cozzi, AE Ruoho.  Complementary interactions of the rod PDE6 inhibitory subunit with the catalytic subunits and transducin.  Soc. Neurosci. Abs., 35, 164.6 (2009)

 

D Fontanilla, M Johannessen, AR Hajipour, NV Cozzi, MB Jackson, AE Ruoho.  The hallucinogen N,N-dimethyltryptamine (DMT) is an endogenous sigma-1 receptor regulator.  Science, 323, 934-937 (2009)

 

SD Brandt, SS Tirunarayanapuram, S Freeman, N Dempster, SA Barker, PF Daley, NV Cozzi, CPB Martins.  Microwave-accelerated synthesis of psychoactive deuterated N,N-dialkylated-[α,α,β,β-d4]-tryptamines.  J. Label. Compd. Radiopharm., 51, 423-429 (2008)

 

NV Cozzi, AT Shulgin, PF Daley, A Gopalakrishnan, LL Anderson, JT Feih, AE Ruoho.  Psychoactive N,N‑dialkyltryptamines modulate serotonin transport by at least two mechanisms.  Soc. Neurosci. Abs., 34, 536.17 (2008)

 

D Fontanilla, M Johannessen, AR Hajipour, A Pal, NV Cozzi, MB Jackson, AE Ruoho.  N,N-dimethyltryptamine (DMT) as an endogenous ligand candidate for the sigma-1 receptor.  Soc. Neurosci. Abs., 34, 660.10 (2008)

 

NV Cozzi, A Gopalakrishnan, LL Anderson, JT Feih, AE Ruoho.  N,N-dialkyltryptamines inhibit plasma membrane and vesicular serotonin transport.  FASEB J., 22, 714.10 (2008)

 

NV Cozzi, KF Foley, D Fontanilla, A Gopalakrishnan, AE Ruoho.  A novel amphetamine-related photoaffinity probe.  FASEB J., 21, 715.2 (2007)

 

RA Sewell, M Baggot, NV Cozzi, R Doblin, R Forte, M Franklin, NM Goldsmith, P Goodwin, C Guillot, J Hanna, J Holmes, I Jerome, S Kumar, CD Lovett, D Merkur, J Onnie-Hay, E Peden, TB Roberts, MA Ruderman, K Sachs, TC van Veen.  So You Want To Be A Psychedelic Researcher?  Entheogen Rev., XV (2), 41-47 (2006)

 

DM Raffel, W Chen, YW Jung, DL Gildersleeve,  NV Cozzi.  [11C]-Phenethylguanidines: transport kinetics and binding affinities for the human norepinephrine transporter.  J. Nucl. Med., 47, 72P (2006)

 

AL Wittenburg, JA O’Connor, DL Evans, YA Evrard, LH Lapczynski, SK Korb, HJ Vernon, SH Nye, NV Cozzi, AJ Dahly-Vernon, HJ Jacob, RJ Roman.  Acceleration of diabetic nephropathy in the T2DN rat.  Amer. Diabetes Assoc. Abs., 66th Annual Scientific Sessions, 2186-PO (2006)

 

JA O’Connor, LH Lapczynski, AJ Dahly-Vernon, YA Evrard, DL Evans, AL Wittenburg, SK Korb, SH Nye, HJ Vernon,  NV Cozzi, HJ Jacob, RJ Roman.  Delay in the progression of diabetic nephropathy in the T2DN rat.  Amer. Diabetes Assoc. Abs., 66th Annual Scientific Sessions, 2185-PO (2006)

 

JA O'Connor, AL Wittenburg, MF Perrine, LH Lapczynski, DL Evans, YA Evrard, SK Korb, AJ Dahly-Vernon, HJ Vernon, SH Nye, NV Cozzi, HJ Jacob, RJ Roman.  Diabetes-induced nephropathy in the T2DN rat.  Amer. Diabetes Assoc. 66th Annual Scientific Sessions, 773-P, (2006)

 

YA Harrington, SK Korb, NV Cozzi, SH Nye, AL Wittenburg, HJ Vernon, DL Evans, JA O’Connor, LH Lapczynski, AJ Dahly-Vernon, JF Baye, RJ Roman, HJ Jacob.  Using PharmGenix rats to detect tacrine hepatotoxicity.  Clin. Pharmacol. Ther., 79, LBOVI-A-2, P82 (2006)

 

NV Cozzi, D Marona-Lewicka, DE Nichols, A Gokin, KF Foley.  Novel aminopropiophenones as antiobesity agents.  Soc. Neurosci. Abs., 31, 533.5 (2005)

 

KF Foley, RA Galbraith, A Gokin, NV Cozzi.  Novel aminopropiophenones as antiobesity agents.  Exp. Biol. 2005 Abs., 7290 (2005)

 

SH Nye, NV Cozzi, JF Baye, A Wittenburg, S Korb, Y Evrard, RJ Roman, HJ Jacob.  Improved rat models for predictive toxicology.  Soc. Tox. Abs., 44, 1897 (2005)

 

NV Cozzi, JF Baye, A Wittenburg, S Korb, MJ Guy, RJ Roman, HJ Jacob, SH Nye.  Pharmgenix: a combinatorial rat panel for predictive toxicology.  Soc. Toxicol. Path., 23, P53 (2004)

 

DM Raffel, W Chen, DL Gildersleeve, YW Jung, NV Cozzi.  Transport of [11C]meta-hydroxyephedrine, [11C]epinephrine, and biogenic amines by the human norepinephrine transporter.  J. Nucl. Med., 45, 216P (2004)

 

JM Dorsey, MG Miranda, NV Cozzi, KG Pinney.  Synthesis and biological evaluation of 2-(4-fluorophenoxy)-2-phenyl-ethyl piperazines as serotonin-selective reuptake inhibitors with a potentially improved adverse reaction profile.  Bioorg. Med. Chem., 12, 1483-1491 (2004)

 

NV Cozzi, KF Foley.  Methcathinone is a substrate for the serotonin uptake transporter.  Pharmacol. Toxicol., 93, 219-225 (2003)

 

KF Foley, NV Cozzi.  Novel aminopropiophenones as potential antidepressants.  Drug Dev. Res., 60, 252-260 (2003)

 

NV Cozzi, KF Foley.  Stimulant and antidepressant-like effects of novel arylketones.  Soc. Neurosci. Abs., 29, 757.11 (2003)

 

KF Foley, NV Cozzi.  Inhibition of transport function and desipramine binding at the human noradrenaline transporter by N‑ethylmaleimide and protection by substrate analogs.  Naunyn-Schmiedeberg's Arch. Pharmacol., 365, 457-461 (2002)

 

KF Foley, ME Van Dort, MK Sievert, AE Ruoho, NV Cozzi. Stereospecific inhibition of monoamine uptake transporters by meta-hydroxyephedrine isomers.  J. Neural Transm. 109, 1229-1240 (2002)

 

NV Cozzi, KF Foley. Rapid and efficient method for suspending cells for neurotransmitter uptake assays.  Biotechniques, 32, 486-492 (2002)

 

NV Cozzi, KF Foley. Methcathinone is a substrate for the serotonin uptake transporter. Soc. Neurosci. Abs., 27, 814.10 (2001)

 

KF Foley, ME Van Dort, NV Cozzi. Stereochemical effects of meta-hydroxyephedrine isomers at monoamine uptake transporters: a structure-activity study. Soc. Neurosci. Abs., 26, 819.20 (2000)

 

RA Sewell, NV Cozzi.  More about Parkinsonism after taking Ecstasy.  N. Engl. J. Med., 341, 1400 (1999)

 

NV Cozzi, MK Sievert, AT Shulgin, P Jacob III, AE Ruoho. Inhibition of plasma membrane monoamine transporters by beta-ketoamphetamines.  Eur. J. Pharmacol., 381, 63-69 (1999)

 

NV Cozzi, KF Foley. Bromine substitution at the ring 3- or 4-position of methcathinone enhances potency at serotonin uptake transporters. Soc. Neurosci. Abs., 25, 678.17 (1999)

 

NV Cozzi, MK Sievert, AT Shulgin, P Jacob III, AE Ruoho. Methcathinone and 2-methylamino-1-(3,4-methylenedioxyphenyl)propan-1-one (methylone) selectively inhibit plasma membrane catecholamine reuptake transporters. Soc. Neurosci. Abs., 24, 341.8 (1998)

 

NV Cozzi, AE Ruoho. Radiosynthesis of [3H]methcathinone, an inhibitor of monoamine reuptake transporters.  J. Label. Compd. Radiopharm., 41, 927-933 (1998)

 

NV Cozzi, AT Shulgin, AE Ruoho. Methcathinone (MCAT) and 2-methylamino-1-(3,4-methylenedioxyphenyl)propan-1-one (MDMCAT) inhibit [3H]serotonin uptake into human platelets. Amer. Chem. Soc. Div. Med. Chem. Abs., 215, 152 (1998)

 

NV Cozzi, S Frescas, D Marona-Lewicka, X Huang, DE Nichols. Indan analogs of fenfluramine and norfenfluramine have reduced neurotoxic potential.  Pharmacol. Biochem. Behav., 59, 709-715 (1998)

 

NV Cozzi. SB-207266, an orally active 5-HT4 receptor antagonist for the treatment of irritable bowel syndrome.  Curr. Res. Serotonin, 3, 115-118 (1998)

 

NV Cozzi. SDZ-HTF-919, a 5-HT4 receptor partial agonist for the treatment of gastrointestinal motility disorder and irritable bowel syndrome. Curr. Drugs Serotonin ID Res. Alert, SDZ-HTF-919, ISSN 1361 6285 (1997)

 

NV Cozzi. A review of the chemistry and pharmacology of CV-5197, a 5-HT2 receptor antagonist. Curr. Drugs Serotonin ID Res. Alert, CV-5197, ISSN 1361 6285 (1997)

 

AJ Boileau, NV Cozzi, P Chen, C Czajkowski. Identification of GABA- and diazepam-responsive regions of the GABAA receptor using gamma 2/alpha 1 subunit chimeras. Soc. Neurosci. Abs., 22, 509.3 (1996)

 

NV Cozzi, DE Nichols. 5-HT2A receptor antagonists inhibit potassium-stimulated gamma-aminobutyric acid release in rat frontal cortex.  Eur. J. Pharmacol., 309, 25-31 (1996)

 

AP Monte, D Marona-Lewicka, NV Cozzi, DL Nelson, DE Nichols. Conformationally restricted tetrahydro-1-benzoxepin analogs of hallucinogenic phenethylamines.  Med. Chem. Res., 5, 651-663 (1995)

 

AP Monte, D Marona-Lewika, NV Cozzi, DE Nichols. Synthesis and pharmacological examination of benzofuran, indan, and tetralin analogs of 3,4-(methylenedioxy)amphetamine.  J. Med. Chem., 36, 3700-3706 (1993)

 

NV Cozzi. Effects of water filtration on marijuana smoke: a literature review. Multidisc. Assoc. Psychedelic Studies, 4 (2), 4-6 (1993)

 

MH Weiler, D Katz, H-J Lee, NV Cozzi, K Das Gupta. Inositol phosphate (IP) accumulation in rat neostriatal slices under conditions used to monitor neurotransmitter release. Soc. Neurosci. Abs., 17, 173.9 (1991)

 

H-J Lee, NV Cozzi, MH Weiler. Age-related differences in the effects of some muscarinic agents on acetylcholine release from rat neostriatal slices.  J. Pharmacol. Exp. Ther., 258, 496-501 (1991)

 

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This page last modified on November 23, 2009